PROMO PRIMO ACQUISTO: 20% di sconto + Guida in regalo

Please accept marketing-cookies to view these contents!.


VEROGHÍ è un alimento che trova le sue origini nella tradizione millenaria della medicina Ayurvedica.

Sin dall’antichità, infatti, i terapeuti avevano osservato le sue straordinarie proprietà curative e riequilibranti.

La scienza moderna sta riscoprendo ciò che l’intuizione e la pratica antica aveva osservato e ha iniziato a studiare questo “superfood” un po’ più da vicino.

Abbiamo raccolto molte delle fonti ad oggi disponibili sul tema ghee e le riproponiamo qui per una più comoda consultazione.

Altre risorse

  • Ríos-Covián D. Intestinal Short Chain Fatty Acids and their Link with Diet and Human Health. Front Microbiol. 2016 Feb 17;7:185
  • Cook YES. Review article: short chain fatty acids in health and disease. Aliment Pharmacol Ther. 1998 Jun;12(6):499-507
  • Xiong Y. Short-chain fatty acids stimulate leptin production in adipocytes through the G protein-coupled receptor GPR41. Proc Natl Acad Sci US A. 2004 Jan 27;101(4):1045-50
  • Den Besten G. Gut-derived short-chain fatty acids are vividly assimilated into host carbohydrates and lipids. Am J Physiol Gastrointest Liver Physiol. 2013 Dec;305(12):G900-10
  • Wong JM. Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol. 2006 Mar;40(3):235-43
  • McOrist AL. Fecal butyrate levels vary widely among individuals but are usually increased by a diet high in resistant starch. J Nutr. 2011 May;141(5):883-9
  • De Fillipis F. High-level adherence to a Mediterranean diet beneficially impacts the gut microbiota and associated metabolome. BMJ 2015 Sept;
  • Den Besten G. The role of short-chain fatty acids in the interplay between diet, gut microbiota, and host energy metabolism. J Lipid Res. 2013 Sep;54(9):2325-40
  • Spiller GA. Effect of purified cellulose, pectin, and a low-residue diet on fecal volatile fatty acids, transit time, and fecal weight in humans. Am J Clin Nutr. 1980 Apr;33(4):754-9
  • Topping DL. Short-chain fatty acids and human colonic function: roles of resistant starch and nonstarch polysaccharides. Physiol Rev. 2001 Jul;81(3):1031-64
  • Rossi M. Fermentation of Fructooligosaccharides and Inulin by Bifidobacteria: a Comparative Study of Pure and Fecal Cultures. Appl Environ Microbiol. 2005 Oct; 71(10): 6150–6158
  • Säemann MD. Anti-inflammatory effects of sodium butyrate on human monocytes: potent inhibition of IL-12 and up-regulation of IL-10 production. FASEB J. 2000 Dec;14(15):2380-2
  • Binder HJ. Role of colonic short-chain fatty acid transport in diarrhea. Annu Rev Physiol. 2010;72:297-313
  • Rabbani GH. Green banana and pectin improve small intestinal permeability and reduce fluid loss in Bangladeshi children with persistent diarrhea. Dig Dis Sci. 2004 Mar;49(3):475-84
  • Vieira EL. Oral administration of sodium butyrate attenuates inflammation and mucosal lesion in experimental acute ulcerative colitis. J Nutr Biochem. 2012 May;23(5):430-6
  • Maslowski KM. Regulation of inflammatory responses by gut microbiota and chemoattractant receptor GPR43. Nature. 2009 Oct 29;461(7268):1282-6
  • Hallert C. Increasing fecal butyrate in ulcerative colitis patients by diet: controlled pilot study. Inflamm Bowel Dis. 2003 Mar;9(2):116-21
  • Di Sabatino A. Oral butyrate for mildly to moderately active Crohn’s disease. Aliment Pharmacol Ther. 2005 Nov 1;22(9):789-94
  • Scheppach W. Treatment of distal ulcerative colitis with short-chain fatty acid enemas. A placebo-controlled trial. German-Austrian SCFA Study Group. Dig Dis Sci. 1996 Nov;41(11):2254-9
  • Vernia P. Combined oral sodium butyrate and mesalazine treatment compared to oral mesalazine alone in ulcerative colitis: randomized, double-blind, placebo-controlled pilot study. Dig Dis Sci. 2000 May;45(5):976-81
  • Breuer RI. Short chain fatty acid rectal irrigation for left-sided ulcerative colitis: a randomized, placebo controlled trial. Gut. 1997 Apr;40(4):485-91
  • Blouin JM. Butyrate elicits a metabolic switch in human colon cancer cells by targeting the pyruvate dehydrogenase complex. Int J Cancer. 2011 Jun 1;128(11):2591-601
  • Scharlau D. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res. 2009 Jul-Aug;682(1):39-53
  • Tang Y. G-protein-coupled receptor for short-chain fatty acids suppresses colon cancer. Int J Cancer. 2011 Feb 15;128(4):847-56
  • Toscani A. Molecular analysis of sodium butyrate-induced growth arrest. Oncogene Res. 1988;3(3):223-38
  • Wong JM. Colonic health: fermentation and short chain fatty acids. J Clin Gastroenterol. 2006 Mar;40(3):235-43
  • Scharlau D. Mechanisms of primary cancer prevention by butyrate and other products formed during gut flora-mediated fermentation of dietary fibre. Mutat Res. 2009 Jul-Aug;682(1):39-53
  • Klampfer L. Oncogenic Ras promotes butyrate-induced apoptosis through inhibition of gelsolin expression. J Biol Chem. 2004 Aug 27;279(35):36680-8
  • Lupton JR. Microbial degradation products influence colon cancer risk: the butyrate controversy. J Nutr. 2004 Feb;134(2):479-82
  • Hioki K. Suppression of intestinal polyp development by low-fat and high-fiber diet in Apc(delta716) knockout mice. Carcinogenesis. 1997 Oct;18(10):1863-5
  • Donohoe DR. A gnotobiotic mouse model demonstrates that dietary fiber protects against colorectal tumorigenesis in a microbiota- and butyrate-dependent manner. Cancer Discov. 2014 Dec;4(12):1387-97
  • Dallas R. Donohoe. A Gnotobiotic Mouse Model Demonstrates that Dietary Fiber Protects Against Colorectal Tumorigenesis in a Microbiota- and Butyrate–Dependent Manner. Cancer Discov. 2014 Dec; 4(12): 1387–1397
  • Bingham SA. Dietary fiber in food and protection against colorectal cancer in the European Prospective Investigation into Cancer and Nutrition (EPIC): an observational study. Lancet. 2003 May 3;361(9368):1496-501
  • Fuchs CS. Dietary fiber and the risk of colorectal cancer and adenoma in women. N Engl J Med. 1999 Jan 21;340(3):169-76
  • Park Y. Dietary fiber intake and risk of colorectal cancer: a pooled analysis of prospective cohort studies. JAMA. 2005 Dec 14;294(22):2849-57
  • Schatzkin A. Dietary fiber and whole-grain consumption in relation to colorectal cancer in the NIH-AARP Diet and Health Study. Am J Clin Nutr. 2007 May;85(5):1353-60
  • Tilg H. Microbiota and diabetes: an evolving relationship. Gut. 2014 Sep;63(9):1513-21
  • Remely M. Effects of short chain fatty acid producing bacteria on epigenetic regulation of FFAR3 in type 2 diabetes and obesity. Gene. 2014 Mar 1;537(1):85-92
  • Yamashita H. Improvement of obesity and glucose tolerance by acetate in Type 2 diabetes Otsuka Long-Evans Tokushima Fatty (OLETF) rats. iosci Biotechnol Biochem. 2007 May;71(5):1236-43
  • Zydowo MM. Acetate-induced changes of adenine nucleotide levels in rat liver. Metabolism. 1993 May;42(5):644-8
  • Jäger S. AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1alpha. Proc Natl Acad Sci US A. 2007 Jul 17;104(29):12017-22
  • Sakakibara S. Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. Biochem Biophys Res Commun. 2006 Jun 2;344(2):597-604
  • Boillot J. Effects of dietary propionate on hepatic glucose production, whole-body glucose utilization, carbohydrate and lipid metabolism in normal rats. Br J Nutr. 1995 Feb;73(2):241-51
  • Tolhurst G. Short-chain fatty acids stimulate glucagon-like peptide-1 secretion via the G-protein-coupled receptor FFAR2. Diabetes. 2012 Feb;61(2):364-71
  • Melmon KL. Inflammatory and immune responses: cell individuality amidst ubiquitous hormonal signals. Johns Hopkins Med J. 1977 Jul;141(1):15-22
  • Alamowitch C. Lack of effect of an acute ileal perfusion of short-chain fatty acids on glucose metabolism in healthy men. Am J Physiol. 1996 Jul;271(1 Pt 1):E199-204
  • Bays H. Reduced viscosity Barley β-Glucan versus placebo: a randomized controlled trial of the effects on insulin sensitivity for individuals at risk for diabetes mellitus. Nutr Metab (London). 2011 Aug 16;8:58
  • Vogt JA. L-rhamnose and lactulose decrease serum triacylglycerols and their rates of synthesis, but do not affect serum cholesterol concentrations in men. J Nutr. 2006 Aug;136(8):2160-6
  • Bourdon I. Postprandial lipid, glucose, insulin, and cholecystokinin responses in men fed barley pasta enriched with beta-glucan. Am J Clin Nutr. 1999 Jan;69(1):55-63
  • Kimura I. Host energy regulation via SCFAs receptors, as dietary nutrition sensors, by gut microbiota. Yakugaku Zasshi. 2014;134(10):1037-42
  • Zhiwei Ang. GPR41 and GPR43 in Obesity and Inflammation – Protective or Causative? Front Immunol. 2016; 7:28
  • Lin HV. Butyrate and propionate protect against diet-induced obesity and regulate gut hormones via free fatty acid receptor 3-independent mechanisms. PLoS One. 2012;7(4):e35240
  • Kondo T. Acetic acid upregulates the expression of genes for fatty acid oxidation enzymes in liver to suppress body fat accumulation. J Agric Food Chem. 2009 Jul 8;57(13):5982-6
  • GE H. Activation of G protein-coupled receptor 43 in adipocytes leads to inhibition of lipolysis and suppression of plasma free fatty acids. Endocrinology. 2008 Sep;149(9):4519-26
  • Zhanguo Gao. Butyrate Improves Insulin Sensitivity and Increases Energy Expenditure in Mice. Diabetes. 2009 Jul; 58(7): 1509–1517
  • Threapleton DE. Dietary fiber intake and risk of cardiovascular disease: systematic review and meta-analysis. BMJ. 2013 Dec 19;347:f6879
  • Yunsheng Ma. Association between dietary fiber and markers of systemic inflammation in the Women’s Heath Initiative Observational Study. Nutrition. 2008 Oct; 24(10): 941–949
  • Pereira MA. Dietary fiber and risk of coronary heart disease: a pooled analysis of cohort studies. Arch Intern Med. 2004 Feb 23;164(4):370-6
  • Lairon D. Dietary fiber intake and risk factors for cardiovascular disease in French adults. Am J Clin Nutr December 2005 vol. 82 no. 6 1185-1194
  • Erkkilä AT. Fiber and cardiovascular disease risk: how strong is the evidence? J Cardiovasc Nurs. 2006 Jan-Feb;21(1):3-8
  • Fushimi T. Dietary acetic acid reduces serum cholesterol and triacylglycerols in rats fed a cholesterol-rich diet. Br J Nutr. 2006 May;95(5):916-24
  • Demigné C. Effect of propionate on fatty acid and cholesterol synthesis and on acetate metabolism in isolated rat hepatocytes. Br J Nutr. 1995 Aug;74(2):209-19
  • Kondo T. Vinegar intake reduces body weight, body fat mass, and serum triglyceride levels in obese Japanese subjects. Biosci Biotechnol Biochem. 2009 Aug;73(8):1837-43
  • Sun J. Neuroprotective Effect of Sodium Butyrate against Cerebral Ischemia/Reperfusion Injury in Mice. Biomed Res Int. 2015;2015:395895
  • Alvaro A. Gene expression analysis of a human enterocyte cell line reveals downregulation of cholesterol biosynthesis in response to short-chain fatty acids. IUBMB Life. 2008 Nov;60(11):757-64
  • Wright RS. Propionate inhibits hepatocyte lipid synthesis. Proc Soc Exp Biol Med. 1990 Oct;195(1):26-9
  • Hara H. Short-chain fatty acids suppress cholesterol synthesis in rat liver and intestine. J Nutr. 1999 May;129(5):942-8
Prova, Gusta, Ama
Seguici anche su: